IV Immunoglobin Therapy in Dermatomyositis

Therapy of calcinosis universalis complicating adult dermatomyositis.

Although frequent in juvenile dermatomyositis, calcinosis is a rare finding in adult dermatomyositis. It has been associated with disease activity and delayed treatment. It is more common in later phases of the disease, in sites under chronic stress and trauma. Calcinosis has been associated with inflammation but information about its pathogeny continues to evolve as we learn more about the und...

Cytomegalovirus infection complicating immunosuppressive therapy for dermatomyositis.

The occurrence of opportunistic infections is not rare during the treatment of connective tissue diseases, including dermatomyositis because of the patient's immunosuppression. We describe here cytomegalovirus (CMV) infection that affected two of our patients with dermatomyositis. CMV infection has not been considered to be a frequent event in dermatomyositis, and its significance for disease p...

Experimental neonatal colibacillosis in cows: immunoglobin classes involved in protection.

Pregnant cows were vaccinated with one of four vaccine preparations to induce passive immunity in their offspring against a homologous oral challenge with Escherichia coli strain B-44. Quantitative assays of specific antibody in colostral whey from both immunized and nonimmunized dams revealed that immunoglobulin G, immunoglobulin A (IgA), and immunoglobulin M (IgM) with anti-O (somatic) activi...

Dermatomyositis in patients with rheumatoid arthritis during adalimumab therapy.

Dermatomyositis-like eruption associated with hydroxyurea therapy: a premalignant condition?

Hydroxyurea (HU) is an anticancer agent that inhibits DNA synthesis through its action on the enzyme ribonucleotide reductase.1 It is used in chronic myeloproliferative diseases such as polycythemia vera, chronic myeloid leukemia, and essential thrombocytosis, although it has also been prescribed to patients with refractory psoriasis.2 We present the case of a 76-year-old woman diagnosed with i...